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Because GLP-1 drugs affect the brain's reward pathways, they may shift how you feel emotionally, including your interest in activities you once enjoyed

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[6] [8] The FDA-approved dosing involves weekly subcutaneous injections, with gradual dose escalation to minimize gastrointestinal side effects

Additionally, semaglutide acts on appetite-regulating centers in the brain, promoting satiety and reducing caloric intake, which facilitates weight loss

Their expanding use among people who are not obese or living with diabetes also raises important questions about long term safety, access, affordability, and appropriate use